Fel Bufonis / Bufonis Jecur
Aliases：Lài Há Má Gān (Toad Liver).
Chán Chú Gān (Toad Liver) is a traditional Chinese medicinal material. It is the liver of Bufo bufo gargarizans Cantor or Bufo melanostictus Schneider, animals belonging to the family Bufonidae. This medicinal material was first recorded in Yilin Zuanyao (Essentials of Medical Compilation).
Efficacy & Actions
Detoxifies and disperses nodules; draws out boils and reduces swelling. This product is good at clearing heat toxins and dispersing sores and carbuncles, making it an excellent remedy for treating carbuncles and furuncles.
Indications
Indicated for carbuncles, furuncles, sores and swellings, snakebites, and measles.
Modern Pharmacology
Modern research has shown that toad liver contains various bioactive components such as bufotoxin, bufotenine, and bufotic acid. The toad liver is an important site for the synthesis and accumulation of bufadienolides (BDs), with content second only to the parotid gland, and the highest concentration found in bile. Pharmacological effects include: Antibacterial effects: Bufotoxin, bufotenine, and other components have broad-spectrum antibacterial activity against various bacteria, fungi, and viruses. Anti-inflammatory effects: Inhibits the release of inflammatory cytokines and alleviates inflammatory responses. Analgesic effects: Exhibits pain-relieving effects. Antitumor effects: Inhibits tumor cell growth and proliferation. Cinobufotalin (extracted from toads) has been shown to have anti-liver cancer effects, involving mechanisms such as regulation of bcl-2/bax and Fas/FasL expression, cell cycle regulation, and inhibition of tumor angiogenesis.
Ingredients
Choline. Ascorbic acid. Xanthine oxidase. Uricase. Tyrosine. Melanin. In addition, it also contains bioactive components such as bufotoxin, bufotenine, and bufotic acid.
Usage & Dosage
For oral administration: decoct in water, 1–2 pieces. Some sources also document 3–5 g. For external use: apply an appropriate amount, crushed and applied topically to the affected area.
Contraindications
This product is toxic; long-term use should be avoided. Use with caution during pregnancy. Use with caution in breastfeeding women. Use with caution in children. Use with caution in patients with liver or kidney insufficiency. Monitor your condition during use; if any discomfort occurs, discontinue use immediately and seek medical attention. Should only be used under the guidance of a qualified physician. Self-collection and handling are strictly prohibited.
Selected Formulas
For measles with poor eruption, delayed eruption, or rapid fading after eruption, with persistent or rising fever (Ganzhou Collection of Simple and Effective Herbal Remedies) Take 1–2 toad livers, decoct in water and drink. One to two doses are sufficient. For furuncles (Jiangxi Herbal Medicine Manual) Take one toad liver, 6g of Dingxiang (Clove), and 6g of Zhusha (Cinnabar). Grind together into powder and apply to the affected area. For snake bites (Qingdao Chinese Herbal Medicine Manual) Take fresh toad liver, crush and apply externally to the wound.
Medicinal Parts
Liver.
Selection & Storage
Use fresh or refrigerate.
